Inherited causes of clonal haematopoiesis in 97,691 complete genomes

Nature, Revealed on-line: 14 October 2020; doi:10.1038/s41586-020-2819-2

Evaluation of 97,691 high-coverage human blood DNA-derived whole-genome sequences enabled simultaneous identification of germline and somatic mutations that predispose people to clonal growth of haematopoietic stem cells, indicating that each inherited and bought mutations are linked to age-related cancers and coronary coronary heart illness.


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